Peptide data sheet
Thymosin Alpha-1
Longevity · Tα1 · TA1 · Thymalfasin
Verdict
promisingfor immune-modulation research; human evidence is strongest outside the US and thin for wellness use
By MrPepTalks Editorial
Reviewed for scientific accuracy · research information, not medical advice
Last updated Reviewed
Quick answer
Thymosin Alpha-1 is a 28-amino-acid peptide fragment the thymus produces naturally. It is commonly researched for how it modulates immune signalling, and it has been studied in humans for immune support alongside certain therapies in some countries. Sold in the US as a research chemical, it is not FDA-approved, and its effects in healthy people are still being studied.
- Class
- Synthetic thymic peptide fragment (28 amino acids)
- Half-life
- Roughly 2 hours (short-acting)
- FDA status
- Not FDA-approved; sold in the US for research use only
- WADA banned?
- No
Which form actually works?
Injectable (subcutaneous, research)
Promising
The injectable route is the one nearly all human research has looked at, which is why it carries the most data. It is also the form most people report using and asking about in communities.
Oral / capsule
Unproven
Peptides this size are generally broken down in the gut, so oral versions are widely considered poorly absorbed. There is little research support for oral Thymosin Alpha-1, and we treat those claims with caution.
Third-Party Testing & Certificate of Analysis (COA)
A certificate of analysis (COA) is a lab document that reports what a specific batch of material actually contains. Reputable research suppliers publish one for every batch, tied to a lot number you can match against the vial you received.
- HPLC — purity
- High-performance liquid chromatography reports purity as a percentage: how much of the sample is the intended compound rather than impurities.
- Mass spectrometry (MS) — identity
- Mass spectrometry confirms identity by measuring the sample's molecular mass, so it matches the peptide the label names.
It also matters who ran the test. In-house results come from the seller's own lab; an independent third-party lab has no stake in the result, so its COA generally carries more weight. Look for a named testing laboratory, a batch or lot number, and a test date that lines up with the vial in hand.
New to reading one? This guide walks through a COA line by line: how to read a peptide COA.
Sources
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All Longevity →Frequently asked questions
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