Peptide data sheet
MOTS-c
Longevity · MOTS-c · MOTSc
Verdict
unprovenfor metabolic and exercise-related research in people
Quick answer
MOTS-c is a 16-amino-acid peptide encoded inside mitochondrial DNA. In lab and animal research it has been studied for how cells handle glucose and energy, and it is often described as an exercise-mimetic candidate. Controlled human trials are essentially absent, so what it does in people is still an open question. It is sold for research use only and is not FDA-approved.
At a glance
- Class
- Mitochondrial-derived peptide (MDP)
- Half-life
- Short in circulation; not well characterized in humans
- FDA status
- Not FDA-approved; sold for research use only
Which form actually works?
Lyophilized research vial
Unproven
The form Circle Peptides and most research suppliers sell. Studied in laboratory settings; there is no established human protocol, and reported experiences from the research community are anecdotes, not evidence.
Read the full MOTS-c verdictThe deep-dive: every study and Pep's honest take.Reconstitution calculatorConcentration and draw-volume math — informational only.