Peptide data sheet


Ipamorelin
Performance · NNC 26-0161
Verdict
unprovenThe unproven label reflects a real preclinical and early-pharmacology signal on growth-hormone release paired with an absence of completed human trials establishing the recovery, body-composition, or healthy-aging outcomes people actually search for.
By MrPepTalks Editorial
Reviewed for scientific accuracy · research information, not medical advice
Last updated Reviewed
Quick answer
Ipamorelin is a small peptide studied as a selective growth-hormone secretagogue: in research it has been associated with a short-lived rise in growth hormone without much movement in other hormones, which is why it is often described as selective. Most of that data is preclinical or early pharmacology, not completed human outcome trials. It is not FDA-approved and is sold for laboratory research use only.
- Class
- Growth-hormone secretagogue (ghrelin / GH-secretagogue-receptor agonist pentapeptide)
- Half-life
- roughly 2 hours (reported)
- FDA status
- Not FDA-approved. Sold as a research chemical for laboratory research use only; it has not been proven safe or effective for human use.
- WADA banned?
- Yes
Which form actually works?
Injectable (subcutaneous)
Unproven
The form nearly all of the research and user accounts describe. It carries whatever research context ipamorelin has, but that context is mostly preclinical and early pharmacology rather than completed human outcome trials, so the label stays unproven.
Oral / capsule
Risky
Peptides like this are broken down in the gut, so an oral version is widely doubted on absorption grounds and is a common marker of a low-quality or mislabeled product. Treat oral ipamorelin claims with extra skepticism.
Third-Party Testing & Certificate of Analysis (COA)
A certificate of analysis (COA) is a lab document that reports what a specific batch of material actually contains. Reputable research suppliers publish one for every batch, tied to a lot number you can match against the vial you received.
- HPLC — purity
- High-performance liquid chromatography reports purity as a percentage: how much of the sample is the intended compound rather than impurities.
- Mass spectrometry (MS) — identity
- Mass spectrometry confirms identity by measuring the sample's molecular mass, so it matches the peptide the label names.
It also matters who ran the test. In-house results come from the seller's own lab; an independent third-party lab has no stake in the result, so its COA generally carries more weight. Look for a named testing laboratory, a batch or lot number, and a test date that lines up with the vial in hand.
New to reading one? This guide walks through a COA line by line: how to read a peptide COA.
Sources
- Raun K, Hansen BS, Johansen NL, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol, 1998.
- Gobburu JV, Agerso H, Jusko WJ, Ynddal L. Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharm Res, 1999.
- Beck DE, Sweeney WB, McCarter MD, et al. Prospective, randomized, controlled, proof-of-concept study of the ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients. Int J Colorectal Dis, 2014.
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