Peptide data sheet
Tesamorelin
Recovery · TH9507 · Tesamorelin acetate
Verdict
promisingThe promising label reflects the human trial data behind the branded drug for one narrow use; research-grade tesamorelin sold for lab use is not the same product and has a thinner safety picture.
By MrPepTalks Editorial
Reviewed for scientific accuracy · research information, not medical advice
Last updated Reviewed
Quick answer
Tesamorelin is a growth-hormone-releasing factor (GHRH) analog commonly researched for how it affects visceral abdominal fat and the growth-hormone/IGF-1 axis. Unlike most research peptides it has real human trial data: that data supported the branded prescription drug Egrifta, FDA-approved for one narrow use. Research-grade tesamorelin sold for lab use is not that product and is not FDA-approved.
- Class
- GHRH analog (growth-hormone-releasing factor)
- Half-life
- roughly 26 to 38 minutes (reported)
- FDA status
- Egrifta (tesamorelin) is FDA-approved for one narrow use (HIV-associated lipodystrophy). Research-grade tesamorelin sold for lab use is a different product intended for laboratory research only.
- WADA banned?
- Yes
Which form actually works?
Injectable (subcutaneous)
Promising
The form the human trials and the branded prescription drug used. People report the effect timing and the reported side effects here, and it carries the most research context of any form.
Oral or transdermal
Unproven
You will see it pitched as capsules or creams. There is little consistent human data that these routes deliver an intact peptide, so treat those formats as unproven marketing rather than a studied option.
Third-Party Testing & Certificate of Analysis (COA)
A certificate of analysis (COA) is a lab document that reports what a specific batch of material actually contains. Reputable research suppliers publish one for every batch, tied to a lot number you can match against the vial you received.
- HPLC — purity
- High-performance liquid chromatography reports purity as a percentage: how much of the sample is the intended compound rather than impurities.
- Mass spectrometry (MS) — identity
- Mass spectrometry confirms identity by measuring the sample's molecular mass, so it matches the peptide the label names.
It also matters who ran the test. In-house results come from the seller's own lab; an independent third-party lab has no stake in the result, so its COA generally carries more weight. Look for a named testing laboratory, a batch or lot number, and a test date that lines up with the vial in hand.
New to reading one? This guide walks through a COA line by line: how to read a peptide COA.
Sources
- Falutz J, Allas S, Blot K, et al. Metabolic effects of a growth hormone-releasing factor (tesamorelin) in patients with HIV: phase-3 RCT. N Engl J Med 2007;357(23):2359-70.
- Stanley TL, Feldpausch MN, Oh J, et al. Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial. JAMA 2014;312(4):380-89.
- Clinical Review Report: Tesamorelin (Egrifta) — for HIV-associated lipodystrophy (CADTH Common Drug Review). NCBI Bookshelf NBK539127.
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