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Peptide data sheet

GHRP-2

GHRP-2

Performance · Pralmorelin · KP-102 · GHRP2

Verdict

unproven

as a physique or aging-related agent

By MrPepTalks Editorial

Reviewed for scientific accuracy · research information, not medical advice

Last updated Reviewed

Quick answer

GHRP-2 (pralmorelin) is a synthetic growth hormone releasing peptide that acts on the ghrelin receptor to prompt the pituitary to release growth hormone. Early human studies measured real, short-term rises in GH and IGF-1 markers, which is why it was explored as a GH-testing tool. It is not approved by regulators, is sold for research use only, and reported effects include higher cortisol, prolactin, and appetite. The verdict stays Unproven for physique or aging-related use.

At a glance
Class
Growth hormone secretagogue (ghrelin-receptor agonist)
Half-life
Short — roughly 15 to 30 minutes reported in pharmacokinetic studies
FDA status
Not FDA-approved; sold for research use only
WADA banned?
Yes

Which form actually works?

Injectable (research vial)

Unproven

The form studied in the human GH-response and diagnostic literature. It moves GH markers short-term, but human data on physique or aging-related outcomes is missing, and sourcing is gray-market.

Oral / nasal

Unproven

Sometimes marketed in these forms, but peptide bioavailability by these routes is poorly characterized and there is little supporting human data. Considered unproven.

Third-Party Testing & Certificate of Analysis (COA)

A certificate of analysis (COA) is a lab document that reports what a specific batch of material actually contains. Reputable research suppliers publish one for every batch, tied to a lot number you can match against the vial you received.

HPLC — purity
High-performance liquid chromatography reports purity as a percentage: how much of the sample is the intended compound rather than impurities.
Mass spectrometry (MS) — identity
Mass spectrometry confirms identity by measuring the sample's molecular mass, so it matches the peptide the label names.

It also matters who ran the test. In-house results come from the seller's own lab; an independent third-party lab has no stake in the result, so its COA generally carries more weight. Look for a named testing laboratory, a batch or lot number, and a test date that lines up with the vial in hand.

New to reading one? This guide walks through a COA line by line: how to read a peptide COA.

Sources

  1. Laferrère B, et al. Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men. J Clin Endocrinol Metab. 2005;90(2):611-614.
  2. Sigalos JT, Pastuszak AW. The Safety and Efficacy of Growth Hormone Secretagogues. Sex Med Rev. 2018;6(1):45-53.
  3. World Anti-Doping Agency. The Prohibited List (Section S2 — Peptide Hormones, Growth Factors, Related Substances and Mimetics; GHRP-2/pralmorelin prohibited).

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