Peptide data sheet
SNAP-8
Skincare · Acetyl Octapeptide-1 · Acetyl Glutamyl Heptapeptide-1
Verdict
promisingfor topical expression lines
Quick answer
SNAP-8 (Acetyl Octapeptide-1) is a topical cosmetic peptide commonly researched for softening expression lines, marketed as a needle-free Botox alternative. Early studies and manufacturer data reported reduced wrinkle depth, earning a Promising verdict for the topical form. It is a cosmetic ingredient, not FDA-approved, and how much of a large peptide crosses intact skin is still debated.
- Class
- Acetylated octapeptide (SNAP-25 mimetic)
- Half-life
- Not established for topical cosmetic use
- FDA status
- Cosmetic ingredient (topical); not FDA-approved as a drug
- WADA banned?
- No
Which form actually works?
Topical (serum / cream)
Promising
The form with the actual data. Manufacturer and early studies reported reduced wrinkle depth on expression lines. Legal, over-the-counter, and where the evidence sits.
Injectable (research vial)
Unproven
No human efficacy data supports the injectable route, and it carries gray-market sourcing risk. The peptide was studied and sold as a topical cosmetic, not as a research vial.