Peptide data sheet
Pemvidutide
GLP-1 · ALT-801
Verdict
promisingobesity / MASH (investigational, early human trials)
By MrPepTalks Editorial
Reviewed for scientific accuracy · research information, not medical advice
Last updated Reviewed
Quick answer
Pemvidutide (ALT-801) is an investigational GLP-1/glucagon dual receptor agonist developed by Altimmune. It is commonly researched for weight management and metabolic dysfunction-associated steatohepatitis (MASH), with early Phase 2 human trials reporting notable weight change. It is not FDA-approved, is not available for human use outside trials, and its longer-term safety and effects are still being studied.
- Class
- GLP-1 / glucagon dual receptor agonist
- Half-life
- supports once-weekly dosing (per developer reports)
- FDA status
- Not FDA-approved (investigational)
Which form actually works?
Investigational injectable (trial use)
Promising
The form studied in Altimmune's Phase 2 obesity and MASH programs. Early data has been reported by the sponsor; results have not been confirmed in large Phase 3 trials, and it is not available or approved for human use.
Gray-market vial
Risky
Any product sold as pemvidutide outside a clinical trial is unregulated. Purity, sterility, and labeled strength are unverified, and this is where the real supply-safety danger sits.
Third-Party Testing & Certificate of Analysis (COA)
A certificate of analysis (COA) is a lab document that reports what a specific batch of material actually contains. Reputable research suppliers publish one for every batch, tied to a lot number you can match against the vial you received.
- HPLC — purity
- High-performance liquid chromatography reports purity as a percentage: how much of the sample is the intended compound rather than impurities.
- Mass spectrometry (MS) — identity
- Mass spectrometry confirms identity by measuring the sample's molecular mass, so it matches the peptide the label names.
It also matters who ran the test. In-house results come from the seller's own lab; an independent third-party lab has no stake in the result, so its COA generally carries more weight. Look for a named testing laboratory, a batch or lot number, and a test date that lines up with the vial in hand.
New to reading one? This guide walks through a COA line by line: how to read a peptide COA.
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