Peptide data sheet
Hexarelin
Performance · Examorelin
Verdict
unprovenno human outcome data
By MrPepTalks Editorial
Reviewed for scientific accuracy · research information, not medical advice
Last updated Reviewed
Quick answer
Hexarelin is a synthetic six-amino-acid growth-hormone-releasing peptide, commonly researched for its strong effect on GH release and for a separate cardiac-tissue signal in animal models. Human outcome data is thin, so the verdict stays Unproven. It is not FDA-approved and is prohibited in sport under the WADA growth-hormone-secretagogue category.
- Class
- Growth-hormone-releasing peptide (GHRP-6 analog)
- Half-life
- Short (reported in the range of tens of minutes in early human studies)
- FDA status
- Not FDA-approved (sold as a research chemical)
- WADA banned?
- Yes
Which form actually works?
Injectable (subcutaneous research vial)
Unproven
The form used in most published animal and early human research. Studied for GH release, but long-term human outcome data is absent and gray-market sourcing adds contamination risk.
Intranasal
Unproven
An intranasal route appeared in some early pharmacology work, but human outcome evidence for it is minimal and it is not an established delivery form.
Third-Party Testing & Certificate of Analysis (COA)
A certificate of analysis (COA) is a lab document that reports what a specific batch of material actually contains. Reputable research suppliers publish one for every batch, tied to a lot number you can match against the vial you received.
- HPLC — purity
- High-performance liquid chromatography reports purity as a percentage: how much of the sample is the intended compound rather than impurities.
- Mass spectrometry (MS) — identity
- Mass spectrometry confirms identity by measuring the sample's molecular mass, so it matches the peptide the label names.
It also matters who ran the test. In-house results come from the seller's own lab; an independent third-party lab has no stake in the result, so its COA generally carries more weight. Look for a named testing laboratory, a batch or lot number, and a test date that lines up with the vial in hand.
New to reading one? This guide walks through a COA line by line: how to read a peptide COA.
Sources
- Ghigo E, Arvat E, Gianotti L, et al. Growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, after intravenous, subcutaneous, intranasal, and oral administration in man. J Clin Endocrinol Metab. 1994;78(3):693-698.
- Bodart V, Febbraio M, Demers A, et al. CD36 mediates the cardiovascular action of growth hormone-releasing peptides in the heart. Circ Res. 2002;90(8):844-849.
- World Anti-Doping Agency. The Prohibited List (S2: Peptide Hormones, Growth Factors, Related Substances and Mimetics — growth hormone secretagogues / GHRPs including hexarelin).
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